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Andarine (S4)
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Andarine (S4)
Androgens & SARMs
About
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An older oral SARM researched for lean tissue, noted for a temporary, reversible vision side effect.
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Class
SARM (research)
Route
Oral
Typical range
25 to 50 mg/day
Half-life
About 4 hours
Schedule
Often split through the day
Educational summary. See Sources & research below for the underlying studies.
What it is
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Andarine (S4) is one of the older SARMs. It is an investigational research compound, not an approved medicine, sold for research only.
• Status: investigational, sold for research only
• Researched for lean tissue and bone
• Oral, so there is no injection
How it works
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A SARM that binds androgen receptors with a short duration of action.
• Signals muscle and bone tissue
• Short half-life, so research often splits the daily amount
• Can suppress natural hormones
Dosing and mixing
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Reference tiers only. Track the dose you are already taking.
Low
About 25 mg per day
FOR The most conservative researched amount
BENEFIT Often picked as the lower-exposure receptor-signaling tier
Standard
About 25 to 50 mg per day
FOR The commonly cited research range
BENEFIT The range most often cited in research discussions
High
About 50 mg per day
FOR Upper end seen in some research
BENEFIT A higher-exposure tier, with more vision side effects reported
Schedule: Often split into smaller amounts through the day because the half-life is short. Research discusses several weeks, then time off.
Beginner ramp: Start at the lowest researched amount and stay conservative.
Ranges are reference only, not a recommendation. See Sources & research below.
How to take it
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Taken by mouth, often split through the day. There is no injection site.
• Measure liquids carefully, concentrations vary
• Research often divides the daily amount into two or three
• Pair any research with a knowledgeable clinician
What to expect
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Weeks 1 to 2
Some report a temporary yellow tint to vision or trouble adjusting to dark, which reverses after stopping.
Weeks 3 to 6
Lean tissue and strength are commonly discussed here.
After use
Research notes a recovery period for natural hormones.
Side effects
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Commonly reported
• Temporary, reversible vision changes (yellow tint, night vision)
• Can lower natural testosterone
See a clinician if
• Vision changes that do not resolve after stopping
• Yellowing of the skin or eyes
• Any reaction that worries you
Storage
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Keep it stable and clearly labeled.
• Store cool and out of direct light
• Keep away from children and pets
• Label clearly as a research compound
Sources & research
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Vision effect
Andarine research describes a temporary, reversible vision side effect. It is not an approved medicine.
Sources are provided for education and are not exhaustive. Where a source names a specific trial or journal it is shown above; always confirm with a licensed clinician.
Educational and research information only. Not medical advice. Always confirm dosing and safety with a licensed clinician.
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