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Cardarine (GW-501516)
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Cardarine (GW-501516)
Androgens & SARMs
About
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An oral PPAR-delta agonist (it switches on a receptor that controls how you burn fuel), often grouped with SARMs, studied for endurance and fat metabolism.
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Class
PPAR-delta (research)
Route
Oral
Typical range
10 to 20 mg/day
Half-life
About 24 hours
Schedule
Once daily
Educational summary. See Sources & research below for the underlying studies.
What it is
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Cardarine (GW-501516) is not a SARM. It is a PPAR-delta receptor agonist that is often grouped with them. It is an investigational research compound, not an approved medicine, sold for research only.
• Status: investigational, sold for research only
• Researched for endurance and fat metabolism, not muscle building
• Oral, so there is no injection
How it works
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It acts on the PPAR-delta pathway that governs how cells burn fuel.
• Shifts energy use toward burning fat
• Studied for endurance and lipid markers
• Does not act on androgen receptors
Dosing and mixing
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Reference tiers only. Track the dose you are already taking.
Low
About 10 mg per day
FOR The most conservative researched amount
BENEFIT Often picked as the lower-exposure tier in metabolic research discussions
Standard
About 10 to 15 mg per day
FOR The commonly cited research range
BENEFIT The range most often cited in research discussions
High
About 20 mg per day
FOR Upper end seen in some research
BENEFIT A higher-exposure tier with the most limited long-term safety data
Schedule: Once daily by mouth, often timed before activity. Research discusses several weeks, then time off.
Beginner ramp: Start at the lowest researched amount and stay conservative.
Ranges are reference only, not a recommendation. See Sources & research below.
How to take it
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Taken by mouth, usually once a day. There is no injection site.
• Measure liquids carefully, concentrations vary
• Some research times it before activity
• Pair any research with a knowledgeable clinician
What to expect
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Weeks 1 to 2
Some report steadier endurance during activity.
Weeks 3 to 6
Endurance and lipid markers are commonly discussed here.
Keep in mind
Long-term animal studies raised safety concerns at high doses.
Side effects
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Commonly reported
• Generally reported as well tolerated short term
See a clinician if
• Any new or unusual symptom
• Lasting fatigue
• A reaction that worries you
Storage
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Keep it stable and clearly labeled.
• Store cool and out of direct light
• Keep away from children and pets
• Label clearly as a research compound
Sources & research
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Safety note
Long-term high-dose animal studies reported cancer concerns, which ended its development. Treat the safety picture with caution.
Sources are provided for education and are not exhaustive. Where a source names a specific trial or journal it is shown above; always confirm with a licensed clinician.
Educational and research information only. Not medical advice. Always confirm dosing and safety with a licensed clinician.
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